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In vitro antitumor activity of the compounds 109a–109d toward A-549, HCT-116, Hep-G2 and MCF-7 cancer cell lines.
| Compounds | % Inhibitory Activity against Tumor Cell Lines at 300 μM | |||
|---|---|---|---|---|
| A-549 | HCT-116 | Hep-G2 | MCF-7 | |
| 109a | 7.2 | 81.1 | 40.0 | 35.1 |
| 109b | 38.3 | 65.5 | 60.8 | 49.4 |
| 109c | 0.0 | 35.3 | 41.7 | 39.5 |
| 109d | 48.8 | 49.9 | 62.4 | 59.6 |
| Doxorubicin | 84.1 ± 12.6 | 111.7 ± 20.5 | 63.6 ± 9.4 | 163.8 ± 10.1 |
