Table 3.

Results of p-values obtained from statistical analysis of five antibiotics showing highest susceptibility percentages and variables “isolation source”, “Castilla y León provinces”, and “time frames” (set up according to the number of isolates existing each year).

Antibiotic Parameters Tested	Rate of Susceptibility (%)	p-Value	Antibiotic Parameters Tested	Rate of Susceptibility (%)	p-Value
Amikacin			Tetracycline
Humans	96.8	0.114	Humans	93.5	0.234
Hares	100		Hares	99.0
Voles	100		Voles	97.4
Palencia	100	--- (ns)	Palencia	98.3	0.767
Valladolid	100		Valladolid	96.1
Zamora	100		Zamora	97.2
1997–1998	100	< 0.01 *	1997–1998	90.0	0.009 *
1999–2006	75		1999–2006	100
2007–2010	100		2007–2010	100
2014–2015	100		2014–2015	100
2016–2017	100		2016–2017	86.7
2019–2020	100		2019–2020	100
Gentamicin			Ciprofloxacin
Humans	100	0.594	Humans	100	0.594
Hares	99.0		Hares	99.0
Voles	97.4		Voles	97.4
Palencia	98.3	0.482	Palencia	98.3	0.713
Valladolid	100		Valladolid	98.0
Zamora	100		Zamora	100
1997–1998	100	0.679	1997–1998	100	0.392
1999–2006	100		1999–2006	100
2007–2010	97.1		2007–2010	98.6
2014–2015	100		2014–2015	100
2016–2017	100		2016–2017	93.3
2019–2020	100		2019–2020	100
Tobramycin
Humans	100	0.446
Hares	96.9
Voles	94.7
Palencia	96.7	0.329
Valladolid	94.1
Zamora	100
1997–1998	100	0.712
1999–2006	100
2007–2010	95.7
2014–2015	97.4
2016–2017	93.3
2019–2020	100

Ns, not significant; * Significant p-values are highlighted in red.