Table 1.
Baseline characteristic of the study population (N = 509)
| Demographics | All Patients (509) |
|---|---|
| Mean age, y (SD) | 62 (9.2) |
| Male, N (%) | 365 (71.7) |
| Education, y (SD) | 15 (3) |
| Medical History | |
| Dyslipidemia, N (%) | 428 (84.0) |
| Obesity, N (%) | 412 (80.9) |
| Hypertension, N (%) | 401 (78.7) |
| Diabetes mellitus, N (%) | 161 (31.6) |
| History of heart failure, N (%) | 67 (13.1) |
| History of myocardial infarction, N (%) | 186 (36.6) |
| Presence of angiographic atherosclerosis, N (%) | 31 (13.1) |
| Presence of positive stress test, N (%) | 270 (53.0) |
| Atrial fibrillation, N (%) | 23 (4.5) |
| Mean body mass index (SD) | 29.6 (5.0) |
| Mean glomerular filtration rate (mL/min) (SD) | 94.8 (31.2) |
| Mean left ventricular ejection fraction, (SD) | 53.0 (11) |
| Median number of diseased coronary arteries (IQR) | 1 (1–2) |
| Mean Gensini angiographic severity score, (SD) | 44 (51) |
| Medications, N (%) | |
| Aspirin | 430 (84.4) |
| B-Blocker | 382 (75.3) |
| Statins | 437 (85.8) |
| Angiotensin-converting enzyme inhibitors | 250 (49.1) |
| Circulating progenitor cell counts (cells/mL), mean (SD) | |
| CD34+ | 1972 (1402) |
| CD34+/CXCR4+ | 862 (721) |
| CD34+/VEGFR2+ | 12 (9) |
| CD34+/CD146+ | 10 (8) |
| Memory Function, mean (SD) | |
| Immediate Verbal Memory (score points) | 10.4 (3.3) |
| Delayed Verbal Memory (score points) | 7.5 (3.7) |
| Verbal Memory consolidation, % | 68.2 (18.2) |
| Immediate Visual Reproduction (score points) | 8.7 (4.7) |
| Delayed Visual Reproduction (score points) | 8.3 (4.7) |
| Visual Reproduction consolidation, % | 86.3 (15) |
| Trail-A (s) | 42 (19) |
| Trail-B (s) | 101 (49) |
Immediate Verbal Memory (minimum 2.1, maximum 20), Delayed Verbal Memory (minimum 2.1, maximum 20), Verbal Memory consolidation (minimum 0, maximum 100), Immediate Visual Reproduction (minimum 0, maximum 20), Delayed Visual Reproduction (minimum 0, maximum 19.5), Visual Reproduction consolidation (minimum 0, maximum 100), Trail-A (minimum 15, maximum 164), Trail-B (minimum 20, maximum 503). A higher score in verbal and logical memory scales indicates a better cognitive function, while lower scores on the Trail-A and B tests indicate better cognitive function.