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Focality of papillary thyroid cancer in the 63 NOD TPO-CRE-ER-BRAFv600E mice of the 16-week cohort, according to the experimental group (concomitant, pre-existing, or no iodine-exacerbated thyroiditis)
| Papillary thyroid cancer foci | ||||
|---|---|---|---|---|
| Mice (n) | 0 | 1 | ≥2 | |
| Concomitant IET | ||||
| Tamoxifen | 12 | 0 | 3 | 9 |
| Corn oil | 8 | 8 | 0 | 0 |
| Pre-existing IET | ||||
| Tamoxifen | 12 | 7 | 5 | 0 |
| Corn oil | 7 | 6 | 1 | 0 |
| No IET | ||||
| Tamoxifen | 11 | 1 | 3 | 7 |
| Corn oil | 13 | 12 | 1 | 0 |
Abbreviation: IET, iodine exacerbated thyroiditis.
