Table 2.
Median relative abundances (%) of bacterial groups before (T0) and after (T2) two weeks of vitamin C supplementation.
| Bacterial Group | T0 | T2 | p-Value |
|---|---|---|---|
| Bacteroidetes | 5.97 [4.88;8.87] | 3.09 [2.14;4.77] | 0.004 |
| Ruminococci Clostridium group XIVa | 2.06 [1.28;2.82] | 2.66 [1.92;3.13] | 0.048 |
| Bifidobacterium | 1.86 [1.10;3.77] | 3.29 [1.65;5.61] | 0.272 |
| Blautia | 9.68 [7.67;11.8] | 11.3 [10.1;14.5] | 0.035 |
| Ruminococcaceae (-F. prausnitzii) | 16.0 [12.1;17.8] | 13.0 [7.6;15.5] | 0.035 |
| Enterococci | 0.40 [0.22;0.51] | 0.13 [0.07;0.18] | 0.009 |
| Veillonella-Dialister | 0.40 [0.04;0.96] | 0.44 [0.13;1.46] | 0.300 |
| Lachnospiraceae (other) | 12.7 [9.71;16.6] | 16.2 [13.8;17.6] | 0.013 |
| Rest group | 15.8 [14.2;20.0] | 13.2 [10.4;16.4] | 0.510 |
| Roseburia | 5.26 [2.77;8.81] | 5.54 [4.38;9.67] | 0.140 |
| Faecalibacterium prausnitzii | 14.9 [11.4;17.7] | 12.0 [10.3;17.8] | 0.551 |
| Gemmiger formicilis | 3.96 [2.51;6.59] | 1.86 [0.81;3.68] | 0.013 |
| Prevotella copri | 0.01 [0.002;3.39] | 0.003 [0.001;3.01] | 0.221 |
| Collinsella aerofaciens | 0.49 [0.26;0.98] | 0.69 [0.44;1.49] | 0.363 |
| Intestinibacter bartlettii | 0.19 [0.13;0.90] | 0.14 [0.05;0.56] | 0.158 |
| Barnesiella intestinihominis | 0.16 [0.12;0.24] | 0.11 [0.06;0.16] | 0.638 |
| Holdemanella biformis | 0.001 [0.00;0.54] | 0.004 [0.00;0.85] | 0.889 |
| Akkermansia muciniphila | 0.13 [0.02;0.28] | 0.07 [0.02;0.12] | 0.258 |
| Christensenella minuta | 0.05 [0.04;0.09] | 0.03 [0.01;0.08] | 0.683 |
| Streptococcus thermophilus | 0.51 [0.33;0.78] | 0.25 [0.16;0.49] | 0.096 |
Data are presented as median (interquartile range, IQR) of relative abundances (%) at baseline (T0) and two weeks after vitamin C supplementation (T2). Nominal p-value for Wilcoxon’s signed-rank test. Significances after adjustment for multiple comparisons (Benjamini–Hochberg method, FDR < 0.1) are indicated in bold. Abbreviations: FDR, false discovery rate; T0, baseline; T2, two weeks after vitamin C supplementation.