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. 2021 Aug 12;10(8):1280. doi: 10.3390/antiox10081280

Figure 5.

Figure 5

Pterostilbene as compared to short hairpin RNA against SREBP2 (shSREBP2) induces higher protein expression of LDLR and lower nuclear accumulation of HNF-1α. (A) Representative Western blot images of the effect of pterostilbene or shSREBP2 on cytoplasmic PCSK9(p), PCSK9(m), LDLR, p-Akt, Akt, and PCSK9(s) in medium and nuclear HNF-1α or SREBP2 proteins. β-actin and HDAC are loading controls. (B) Graphical representation of (A). * p < 0.05; ** p < 0.01; *** p < 0.001.