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. 2021 Aug 20;10(8):1312. doi: 10.3390/antiox10081312

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Fresh, oven-dried, and freeze-dried extracts from S. ramosissima exerted antiproliferative effects in a dose-dependent manner after exposition for 24 h. Dose-response curves of the antiproliferative effect induced by the (a) freeze-dried extract, (b) oven-dried extract, and (c) fresh extract. (d) EC₅₀ values of the antiproliferative response induced by the fresh (EC₅₀ =15.82 ± 2.65 mg/mL), oven-dried (EC₅₀ = 17.56 ± 1.05 mg/mL), and freeze-dried (EC₅₀ = 17.24 ± 1.36 mg/mL) extracts in HT29 cells (cell model of CRC) did not show significant differences. Results shown are means of at least three independent experiments performed in triplicates ± SD. (*)represent the existence of statistical difference between that dose and the previous one, using one-way ANOVA for multiple comparisons by Tukey’s test (p < 0.05).