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Phenotypic characterization of the aging knock-in mouse model. (A) Percent of survival in the aging mice (Aged and Aged NOX5). n = 13–19. (B) Mice weight (g) evolution in the Aged and Aged NOX5 groups. n = 13–19. (C) Systolic blood pressure (mmHg) alterations in the Aged and Aged NOX5 groups. n = 13–19. The results are expressed as the mean ± SEM. Aged: CRE+/− aging mice and Aged NOX5: NOX5+/−CRE+/− aging mice.
