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. 2021 Jul 28;8(8):108. doi: 10.3390/bioengineering8080108

Figure 6.

Figure 6

Production of BLC-containing RAFT constructs using RHPAs. (A) Shows a schematic of the RAFT process using RHPAs which are placed on top of a collagen hydrogel in a 24-well plate and incubated for 15 min. This will allow wicking of liquid from the hydrogel. RHPAs are then removed, and the RAFT construct remains at the bottom of the well. (B) Shows a schematic pattern of topography of micro-ridges on the base of RHPAs whiles. (C) Shows SEM images of a RAFT construct showing four different topologies on the same surface. (D) Shows the SEM images of the protruding micro-ridges of variable depth on the RHPA surface and corresponding BLCs produced in the surface of the RAFT constructs. Scale bars, C: 1 mm, D: 100 µm [39].