Table 3.
Linear regression model of MTD, PVT and Aggressiveness Index score as categorical. All models on HDL and LDL categories combined.
MTD (cm) | PVT (No/Yes) | Aggressiveness Index score (4/≥5) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | β | se(β) | p-value | 95% C.I. | OR | se(OR) | p-value | 95% C.I. | OR | se(OR) | p-value | 95% C.I. | |||
HDL* | & | LDL¥ | |||||||||||||
High | Low | (Ref. category) | 1 | 1 | 1 | ||||||||||
High | High | 1.25 | 1.24 | 0.31 | −1.19 to 3.70 | 1.14 | 0.79 | 0.85 | 0.29 to 4.45 | 1.08 | 0.78 | 0.92 | 0.26 to 4.43 | ||
Low | Low | 1.25 | 0.33 | <0.001 | 0.60 to 1.91 | 1.25 | 0.25 | 0.26 | 0.85 to 1.84 | 1.11 | 0.21 | 0.56 | 0.77 to 1.61 | ||
Low | High | 3.20 | 0.77 | <0.001 | 1.68 to 4.72 | 3.04 | 1.29 | 0.009 | 1.32 to 6.97 | 12.91 | 13.31 | 0.01 | 1.71 to 97.42 | ||
HDL (mg/dL): High (0), [≥50(F)]/[≥40(M)]; Low (1), [<50(F)]/[<40(M)];
LDL (mg/dL): Low (0), <160; High (1), ≥160. Abbreviations: β, coefficient; se (β), standard error of coefficient; OR, Odds-Ratio; se (OR), standard error of Odds-Ratio; MTD, Maximum Tumor Diameter; PVT, Portal Vein Thrombosis; HDL, High Density Lipoprotein Cholesterol; LDL, Low Density Lipoprotein Cholesterol. Aggressiveness Index as sum of scores: MTD (in terciles): MTD<4.5; 4.5≤MTD≤9.6; MTD>9.6; scores 1, 2, 3 respectively; AFP (cut-off): AFP<100; 100≤AFP≤1000; AFP>1000 ng/ml; scores 1, 2, 3 respectively; PVT (No/Yes): PVT (No); PVT (Yes); scores 1, 3 respectively; Tumor Nodules (number): Nodules≤3; Nodules>3; scores 1, 3 respectively