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(A) Rectal temperature and (B) bacteremia of mice treated or not with CL316,243 (1 mg/kg/day; 1 week) were monitored for 48 hours after infection by E. coli. (C) Mice plasma and scWAT explant leptin levels at the end of experiment. The results are displayed as independent values (dots) and the mean ± SD. n = 8 (mice and plasma) or 4 (scWAT explants). * p<0.05.
