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IL-1β (A) and IL-1RA (B) protein levels were assessed in plasma (upper panel) and in the media of iBAT (middle panel) and scWAT (lower panel) explants from mice that were treated for 1 week with CL316,243 daily (1 mg/kg/day) or vehicle only (NaCl), and with or without E. coli infection for 48 hours. The results are displayed as independent values (dots) and the mean ± SD. n = 8 (plasma) or 4 (explant). * p<0.05.
