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. 2021 Aug 26;17(8):e1009800. doi: 10.1371/journal.ppat.1009800

Fig 11. SARS-CoV-2 Δ382 mutant does not suppress MAVS-induced IFN-production.

Fig 11

(A) Alteration of ORF7b protein sequence as a consequence of a 382bp deletion in SARS-CoV-2. The residues in red show the predicted transmembrane domain. The star represents a stop-termination codon. (B) qPCR was performed (as described in Fig 4) comparing MAVS-induced suppression of IFN mRNA levels by wild-type (WT) SARS-CoV-2 ORF7b and mutant ORF7b-Δ382. Significance was compared to the GFP positive control, *** P < 0.0001. NS—not significant.