Table 1. Summary of experimental evidence emanating from this study, supporting inhibitory activity of individual SARS-CoV-2 genes in repressing type I and type III IFN production.
| IFNβ-Luc | IFNβ-Luc / Renilla | IFNβ mRNA | IFNβ Protein | IFNλ1 mRNA | IFNλ2/3 mRNA | |
| NSP1 | +++ | - | +++ | +++ | +++ | + |
| NSP5 | +++ | + | ++ | +++ | - | - |
| NSP6 | +++ | +++ | ++ | +++ | ++ | ++ |
| NSP13 | + | +++ | - | + | - | - |
| NSP14 | + | + | - | + | - | - |
| NSP15 | +++ | + | +++ | +++ | +++ | +++ |
| ORF6 | +++ | +++ | +++ | +++ | +++ | ++ |
| ORF7b | +++ | +++ | +++ | +++ | +++ | +++ |
| Inhibition intensity | ||||||
| None | - | |||||
| Weak | + | |||||
| Moderate | ++ | |||||
| Strong | +++ | |||||