Table 4.
Univariate and multivariate linear regression analysis of factors associated with miR-133a-3p levels in AD patients.
| Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
| Independent Factors | Coefficient B | 95% CI | p-Value | Coefficient B | 95% CI | p-Value |
| Age | 0.311 | −0.456–8.088 | 0.078 | |||
| BMI | 0.731 | −9.402–10.865 | 0.884 | |||
| Cigarette smoking status | 145.048 | 47.162–242.933 | 0.005 | 5.009 | −89.911–99.93 | 0.915 |
| Pack/years | 6.3 | 1.311–11.289 | 0.015 | −19.101 | −26.645–−11.556 | <0.0001 |
| Diabetes mellitus | −92.961 | −246.252–60.331 | 0.226 | |||
| Hypertension | 114.022 | 14.066–213.978 | 0.027 | |||
| Cardiac disease | 197.707 | 34.312–361.103 | 0.019 | 33.62 | −66.908–134.147 | 0.499 |
| Obesity | 91.719 | −49.547–232.986 | 0.195 | |||
| ID group (AD/CS− vs. AD/CS+) | 231.769 | 138.676–324.861 | <0.0001 | 613.271 | 422.658–803.884 | <0.0001 |
CI, confidence interval; BMI, body mass index; AD, adenocarcinoma; CS, cigarette smoking.