Figure 2.

Neuroprotective effect of GZM extract against H₂O₂-induced toxicity in HT22 and Neuro-2a cells. MTT and LDH methods were used to analyze cell viability of HT22 (a,c) and Neuro-2a cells (b,d) after treatment with varying concentrations of GZM extract. Cell morphology of HT22 (e) and Neuro-2a (f) were observed under a light microscope (5× magnification). ((H200 and H400 corresponds to 200 and 400 µM H₂O₂, respectively; n = 3). (**** p < 0.0001, DMSO control vs. H₂O₂ treatment alone; ^#### p < 0.0001, H₂O₂ treatment alone vs. H₂O₂ and GZM extract treatment. The details of statistical values are provided in Table S3 (Supplementary Materials).