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. 2021 Aug 19;10(8):800. doi: 10.3390/biology10080800

Figure 3.

Figure 3

Neuroprotective effect of GZM extract against glutamate-induced toxicity in HT22 and Neuro-2a cells. MTT and LDH methods were used to analyze cell viability of HT22 (a,c) and Neuro-2a cells (b,d) after treatment with varying concentrations of GZM extract. Cell morphology of HT22 (e) and Neuro-2a (f) were observed under a light microscope (5× magnification). (G5 and G10 corresponds to 5, 10 mM glutamate; n = 3) **** p < 0.0001, DMSO control vs. glutamate treatment alone; #### p < 0.0001 glutamate treatment alone vs. glutamate and GZM extract treatment. The details of statistical values are provided in Table S4 (Supplementary Materials).