PPI |
protein–protein interaction |
DEG |
differentially expressed genes |
ER |
endoplasmic reticulum |
ERAD |
endoplasmic reticulum associated degradation |
EMT |
epithelial-mesenchymal transition |
MAS |
meiosis activating sterol |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
MVK |
mevalonate kinase |
PMVK |
phosphomevalonate kinase |
MVD |
mevalonate diphosphate decarboxylase |
FDPS |
(2E,6E)-farnesyl diphosphate synthase |
FDFT1 |
farnesyl-diphosphate farnesyltransferase 1 |
SQLE |
squalene epoxidase |
LSS |
lanosterol synthase |
DHCR24 |
24-dehydrocholesterol reductase |
CYP51A1 |
sterol 14-alpha-demethylase |
TM7SF2 |
delta(14)-sterol reductase |
MSMO1 |
methylsterol monooxygenase 1 |
NSDHL |
sterol-4alpha-carboxylate 3-dehydrogenase |
HSD17B7 |
17-beta-estradiol 17-dehydrogenase |
EBP |
cholestenol delta-isomerase |
SC5D |
sterol-C5-desaturase |
DHCR7 |
7-dehydrocholesterol reductase |
ACC |
adrenocortical carcinoma |
BLCA |
bladder urothelial carcinoma |
BRCA |
breast invasive carcinoma |
CESC |
cervical squamous cell carcinoma and endocervical adenocarcinoma |
CHOL |
cholangiocarcinoma |
COAD |
colon adenocarcinoma |
DLBC |
lymphoid neoplasm diffuse large B-cell lymphoma |
ESCA |
esophageal carcinoma |
GBM |
glioblastoma multiforme |
HNSC |
head and neck squamous cell carcinoma |
KICH |
kidney chromophobe renal cell carcinoma |
KIRC |
kidney renal clear cell carcinoma |
KIRP |
kidney renal papillary cell carcinoma |
LAML |
scute myeloid leukemia |
LGG |
brain lower grade glioma |
LIHC |
liver hepatocellular carcinoma |
LUAD |
lung adenocarcinoma |
LUSC |
lung squamous cell carcinoma |
MESO |
mesothelioma |
OV |
ovarian serous cystadenocarcinoma |
PAAD |
pancreatic adenocarcinoma |
PCPG |
pheochromocytoma and paraganglioma |
PRAD |
prostate adenocarcinoma, |
READ |
rectum adenocarcinoma |
SARC |
sarcoma |
SKCM |
skin cutaneous melanoma |
STAD |
stomach adenocarcinoma |
TGCT |
testicular germ cell tumors |
THCA |
thyroid carcinoma |
THYM |
thymoma |
UCEC |
uterine corpus endometrial carcinoma |
UCS |
uterine carcinosarcoma |
UVM |
uveal melanoma |