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. 2021 Jul 26;9(8):895. doi: 10.3390/biomedicines9080895

Table 1.

Interactome browsers for retrieving protein–protein interactions data.

No. Name and Ref. Site Notes
1 Funcoup 5.0 [20] http://FunCoup.sbc.su.se (accessed on 15 March 2021) Evidence type—protein interactions, LLR Score > 2, confidence > 0.9, network: “PPI”, “Complex”
2 Mentha [21] https://mentha.uniroma2.it/ (accessed on 15 March 2021) Evidence type: physical interactions
3 CORUM [22] http://mips.helmholtz-muenchen.de/corum/ (accessed on 15 March 2021) -
4 ExoCarta [23] http://www.exocarta.org/ (accessed on 15 March 2021) -
5 APID [24] http://apid.dep.usal.es (accessed on 15 March 2021) Methods (binary, indirect),
≥1 publication
6 MINT [25] https://mint.bio.uniroma2.it/ (accessed on 16 March 2021) Interaction type: association, physical association
7 SIGNOR 2.0 [26] https://signor.uniroma2.it/ (accessed on 16 March 2021) -
8 HuRI [27] http://www.interactome-atlas.org/ (accessed on 16 March 2021) -
9 IID [28] http://iid.ophid.utoronto.ca (accessed on 16 March 2021) Interaction type: experimental
10 Bioplex Explorer 3.0 [29] https://bioplex.hms.harvard.edu/explorer/ (accessed on 16 March 2021) Interaction probability > 0.9
11 Wiki-Pi [30] https://hagrid.dbmi.pitt.edu/wiki-pi/ (accessed on 16 March 2021) -
12 HIPPIE 2.0 [31] http://cbdm-01.zdv.uni-mainz.de/~mschaefer/hippie/ (accessed on 16 March 2021) Score > 0.6
13 HINT [32] http://hint.yulab.org/ (accessed on 16 March 2021) Binary interaction