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Schematic representation summarizing the literature on the glycocalyx, plasma membrane Na+ transport, and Ca2+-dependent signaling and transcription factors that could be implicated in chronic high salt induced vascular smooth muscle and endothelial cells. ROS: reactive oxygen species; Ca2+/CaM: calcium calmodulin; VSMC: vascular smooth muscle cells. Modified from Bkaily et al., 2021 [2].
