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. 2021 Aug 12;10(8):767. doi: 10.3390/biology10080767

Figure 5.

Figure 5

SHH-CX43 axis induces migration enhancement in human GBM cell line. (a,b) Representative images (a) and migration index (b) of control human U-251 MG cells and U-251 MG exposed to 1 µM of purmorphamine and/or cyclopamine, treated with either vehicle or ioxynil octanoate. (c,d) Representative images (c) and migration index (d) of control human T98-G cells and T98-G exposed to 1 µM of purmorphamine and/or cyclopamine, treated with either vehicle or ioxynil octanoate. Data are shown as mean fold change over 0 hrs ± SEM of n = 3 independent experiments; * p-value < 0.05 and ** p-value < 0.01 versus control; one-way ANOVA with Holm–Šídák post-hoc test.