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. 2021 Aug 25;8(8):e00647. doi: 10.14309/crj.0000000000000647

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© 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 1. — (A) Liver: canalicular cholestasis surrounding the central veins with associated bile duct injury. (B) Liver: zone 3 cholestasis and bile duct injury with patchy hepatocyte necrosis. Hematoxylin and eosin stain. (C) Sigmoid colon: surface epithelium with reactive changes, eosinophilic cytoplasm, and disorganized epithelial cell placement. Rare neutrophils are seen with the underlying lamina propria devoid of the normal glandular elements. (D) Sigmoid colon: ulcerated mucosa replaced with granulation tissue (hematoxylin and eosin stain).