Table 1.

Search strategy applied in PubMed.

Num	Entry terms
1	“Acute ischemic stroke” [MeSH Major Topic]
2	“Brain ischemia ” [MeSH Major Topic]
3	“Cerebral Infarction” [MeSH Major Topic]
4	“Cerebrovascular ischemia ” [Text word]
5	“Brain accident” [Text word]
6	“Infarction, Anterior Cerebral Artery” [Text word]
7	“Infarction, Middle Cerebral Artery” [Text word]
8	“Infarction, Posterior Cerebral Artery” [Text word]
9	“Apoplexy” [Text word]
10	#1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9
11	“Naoxintong” [Text word]
12	“Naoxintong capsule” [Text word]
13	“Buchangnaoxintong” [Text word]
14	#11 or #12 or #13
15	#10 and #14
16	Animals [MeSH Major Topic]
17	Humans [MeSH Major Topic]
18	#16 not #17
19	#15 not #18