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. 2021 Aug 26;398(10302):747–758. doi: 10.1016/S0140-6736(21)01755-4

Figure 2.

Figure 2

Risk factors associated with fatigue or muscle weakness (A), anxiety or depression (B), and diffusion impairment (C) at 12-month follow-up

For the association of disease severity with outcome, age, sex, cigarette smoking, education, comorbidity, corticosteroids, antivirals, and intravenous immunoglobulin were adjusted. For the association of factors including sex, corticosteroid, antiviral, and intravenous immunoglobulin with outcome, the aforementioned variables were all included in the model. When exploring the associations of education and smoking with outcome, the aforementioned variables except for comorbidity, and both comorbidity and disease severity (due to the potential mediation) were included, respectively. Only sex, smoking, and education were adjusted for the association between age and outcome due to the potential mediation of other factors. For the association of comorbidity with outcome, the aforementioned variables except for disease severity were all included. OR (95% CI) for age indicates the risk of fatigue or muscle weakness, anxiety or depression, and diffusion impairment per 10-year age increase. OR=odds ratio.