Fig. 4.

Hierarchical clustering of immune cells in blood based on gene set enrichment analysis. (A) Hierarchical clustering of the regulated pathways of significantly modulated genes in CD4⁺ T cells from different disease states. (B) Hierarchical clustering of the regulated pathways of significantly modulated genes in CD8⁺ T cells from different disease states. (C) Hierarchical clustering of the regulated pathways of significantly modulated genes in CD14⁺ monocytes from different disease states. (D) Hierarchical clustering of the regulated pathways of significantly modulated genes in CD16⁺ monocytes from different disease states. The dendrograms are colored according to the p values; gray cells indicate a lack of significant enrichment.