Figure 4.

Small interfering RNA targeting fatty acid synthase (siFASN) suppressed cell migration and invasion. (a) Relative migration rates of MNK-45 and AGS cells in the anoikis resistance (AR), AR + small interfering RNA negative control (siNC), and AR + siFASN groups were determined by wound healing assay. (b) Relative invasion rates of MNK-45 and AGS cells in the AR, AR + siNC, and AR + siFASN groups were determined by transwell invasion assay. (c) Representative images of the migration of MNK-45 and AGS cell migration in the AR, AR + siNC, and AR + siFASN groups determined by wound healing assay. (d) Representative images of the invasion of MNK-45 and AGS cell invasion in the AR, AR + siNC, and AR + siFASN groups determined by transwell invasion assay. ^{^^^} p <0.001 vs. AR + siNC group. Data were performed as the means ± standard.