Table 2.
The differentially overexpressed exosomal proteins in rheumatoid arthritis.
| Protein name | Accession number | Log2 FC∗ | P value |
|---|---|---|---|
| Immunoglobulin lambda variable 6-57 (IGLV6-57) | P01721 | 1 | 0.02 |
| Immunoglobulin heavy variable 4-28 (IGHV4-28) | A0A0C4DH34 | 1 | 0.04 |
| Serum amyloid P-component (SAP/APCS) | P02743 | 1.05 | 0 |
| Immunoglobulin lambda-like polypeptide 1 (IGLL1) | P15814 | 1.12 | 0 |
| Immunoglobulin lambda variable 1-47 (IGLV1-47) | P01700 | 1.13 | 0.01 |
| Immunoglobulin heavy constant gamma 2 (IGHG2) | P01859 | 1.15 | 0.01 |
| Complement C1q subcomponent subunit A (C1QA) | P02745 | 1.26 | 0.01 |
| Immunoglobulin heavy variable 3-53 (IGHV3-53) | P01767 | 1.3 | 0.04 |
| Immunoglobulin heavy variable 3-49 (IGHV3-49) | A0A0A0MS15 | 1.36 | 0.01 |
| Midasin OS (MDN1) | Q9NU22 | 1.38 | 0.01 |
| Immunoglobulin heavy variable 1-58 (IGHV1-58) | A0A0C4DH39 | 1.44 | 0.05 |
| Coagulation factor XI (F11) | P03951 | 1.51 | 0.01 |
| Immunoglobulin heavy variable 1-8 (IGHV1-8) | P0DP01 | 1.63 | 0.03 |
| Inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) | Q06033 | 1.7 | 0 |
| Complement factor I (CFI) | P05156 | 1.7 | 0 |
| Immunoglobulin heavy variable 1-18 (IGHV1-18) | A0A0C4DH31 | 1.75 | 0 |
| Lipopolysaccharide-binding protein (LBP) | P18428 | 1.78 | 0.01 |
| Immunoglobulin lambda variable 1-40 (IGLV1-40) | P01703 | 1.82 | 0 |
| Immunoglobulin lambda variable 1-36 (IGLV1-36) | A0A0B4J1U3 | 1.96 | 0 |
| CDKN2A-interacting protein OS (CDKN2AIP) | Q9NXV6 | 1.97 | 0.04 |
| Monocyte differentiation antigen CD14 (CD14) | P08571 | 1.97 | 0.01 |
| Immunoglobulin gamma-1 heavy chain (IGγ1HC) | P0DOX5 | 2.02 | 0 |
| Immunoglobulin heavy constant gamma 3 (IGHG3) | P01860 | 2.06 | 0 |
| Immunoglobulin heavy variable 4-34 (IGHV4-34) | P06331 | 2.09 | 0 |
| Immunoglobulin heavy variable 1-69D (IGHV1-69D) | A0A0B4J2H0 | 2.2 | 0.01 |
| Immunoglobulin lambda variable 3-1 (IGLV3-1) | P01715 | 2.2 | 0.01 |
| Immunoglobulin lambda variable 3-19 (IGLV3-19) | P01714 | 2.29 | 0 |
| Complement factor H-related protein 5 (CFHR5) | Q9BXR6 | 2.37 | 0.03 |
| Prospero homeobox protein 1 (PROX1) | Q92786 | 2.39 | 0.04 |
| Immunoglobulin heavy variable 2-26 (IGHV2-26) | A0A0B4J1V2 | 2.42 | 0.03 |
| Tenascin (TNC) | P24821 | 2.75 | 0.03 |
| Cartilage oligomeric matrix protein (COMP) | P49747 | 2.92 | 0.03 |
∗FC: fold change.