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. 2021 Aug 25;18:128. doi: 10.1186/s12984-021-00916-1

Table 1.

Biomechanical descriptors and their trends with stiffness

pL pQ vlb vub
Hip

 Cross-leg diff. in max. hip height

   Cross-leg difference in stepwise maximum hip height

0.666 0.289

 Cross-leg RMS diff. hip angle

   Cross-leg root mean squared difference of stepwise hip angle trajectories

0.421 0.759

 Cross-leg RMS diff. hip moment

   Cross-leg root mean squared difference of stepwise hip moment trajectories

0.066 0.950

 Pelvic tilt variance

   Pelvic tilt variance

2e-4* 0.039 - 2.0 69.1
Knee

 Affected knee ROM

   Affected-side knee range of motion

2e-4* 0.177

 Affected knee peak flex. moment

   Affected-side peak knee flexion moment

6e-13* 0.381

 Affected knee peak ext. moment

   Affected-side peak knee extension moment

0.002 0.508

 Unaffected knee ROM

   Unaffected-side knee range of motion

0.653 0.930

 Unaffected knee peak early flex. angle

   Unaffected-side peak knee flexion angle in the first half of stance phase

2e-16* 0.426

 Unaffected knee peak early ext. moment

   Unaffected-side peak knee extension moment in the first half of stance phase

2e-8* 8e-3 8.2 72.0

 Cross-leg RMS diff. knee angle

   Cross-leg root mean squared difference of stepwise knee angle trajectories

0.451 0.092

 Cross-leg RMS diff. knee moment

   Cross-leg root mean squared difference of stepwise knee moment trajectories

0.546 0.110

 Cross-leg diff. in peak knee ext. moment

   Cross-leg difference of stepwise peak knee extension moments

0.036 0.584
Ankle

 Affected ankle peak DF angle

   Affected-side peak (prosthetic) ankle dorsiflexion angle

3e-33* 0.020 22.4 255

 Affected ankle ROM

   Affected (prosthetic) ankle range of motion

3e-37* 5e-3 40.2 215

 Affected ankle peak PF moment

   Affected-side peak (prosthetic) ankle plantar flexion moment

1e-10* 0.019 7.2 100

 Affected ankle peak power

   Affected-side peak (prosthetic) ankle power

7e-18* 0.334

 Unaffected ankle ROM

   Unaffected-side ankle range of motion

0.576 0.863

 Unaffected ankle peak PF moment

   Unaffected-side peak ankle plantar flexion moment

0.131 0.598

 Cross-leg RMS diff. ankle angle

   Cross-leg root mean squared difference of stepwise ankle angle trajectories

0.182 9e-4* - 18.0 3.95

 Cross-leg RMS diff. ankle moment

   Cross-leg root mean squared difference of stepwise ankle moment trajectories

4e-4* 0.535

 Cross-leg diff. in peak ankle PF moment

   Cross-leg difference of stepwise peak ankle plantar flexion moments

1e-5* 0.167

 Cross-leg diff. in peak ankle power

   Cross-leg difference of stepwise peak ankle powers

0.099 0.991
Other

 Affected step prop. of total stride duration

   Affected-side step duration as a proportion of total stride duration

0.017 0.451

 Affected step prop. of total stride distance

   Affected-side step distance as a proportion of total stride distance

0.276 0.965

Twenty-five descriptors were evaluated for first- and second-order fit with preference-normalized VSPA stiffness. The table shows p-values for the linear (pL) and quadratic (pQ) terms of the LMEM fit to each descriptor. For descriptors with pQ < 0.05, the lower (vlb) and upper (vub) bounds on the 95% CI for the vertex stiffness (percent deviation from preferred) are also shown.

*Indicates significance at the α = 0.05 level (Bonferroni correction for 25 tested hypotheses)