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. 2021 Aug 25;9:177. doi: 10.1186/s40168-021-01098-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Effects of gga-miR-222a on the growth and metabolism of Bacteroides fragilis NCTC9343. A Growth curve of Bacteroides fragilis NCTC9343. B Expression of the BF9343_2953 gene in bacterial culture medium. The relative abundances of the control and gga-miR-222a groups are shown compared to that of the blank group (set as 1). C Methionine concentration in the bacterial culture medium. In the figures, asterisk indicates a significant difference among groups, and significant differences among the means were determined by Tukey’s test (P < 0.05)