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. 2021 Jul 26;5(9):1233–1242. doi: 10.1038/s41559-021-01511-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — Numbers mark the succession of steps taken in the experimental protocol. Text in the boxes next to the numbers describe the experimental step. Arrows with black fill describe steps that are taken for the experimental cultures. Arrows with white fill describe steps that are taken for subsamples of the experimental cultures. The annotated steps were repeated for a total of 16 growth periods.