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. 2021 Jul 26;5(9):1233–1242. doi: 10.1038/s41559-021-01511-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — a, Gentamicin experiment, b, Ciprofloxacin experiment. X-axes represent the time series of the evolution experiment: every point represents the end of a growth period before the next transfer. The Y-axes represent the mean yield of the treatments based on the cell counts obtained from flow cytometry. Error bars represent standard error of mean (8 replicates, 1 in CIP-IC80-k50). Blue: IC20 treatments; Red: IC80 treatments; light colours represent k50 transfers; dark colours represent M5 transfers.

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