Fig. 5.

Concentration for hyaluronic acid in FM and BM. The culture medium of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in the flask is “FM” and that of hUC-MSCs in the bioreactor is “BM.” Effects on HA, Pro-collagen synthesis by FM and BM treats in CCD-986SK cells; and role of FM and BM synthesis in melanoma cells line (SK-MEL-31). Experiments were performed in triplicate. Significant differences between FM and BM and the non-irradiated control were evaluated at ∗P < 0.05 and ∗∗P < 0.01.