Fig. 6.

Effect of BM on UVB-induced production of inhibition of MMP-1 protein in CCD-986SK. The culture medium of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in the flask is “FM” and that of hUC-MSCs in the bioreactor is “BM.” Effect of FM and BM on MMP-1 gene expression. UVB (20 mJ/cm2)-exposed CCD-986SK cells were cultured for 48 h in the presence of control, BM, and FM. Control: the control group was stimulated with UVB with no basic culture medium. Results were expressed as % of GAPDH and data represent the means ± SD. Significant differences between FM and BM and the control were evaluated at ∗P < 0.01.