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. 2021 Aug 26;11:17268. doi: 10.1038/s41598-021-96655-3

Table 4.

Acute procedural results. Global and per vein application analysis.

Overall
Total veins (n) 6715
Total applications 12,491
Applications per vein (n) 1.8 ± 1.11
Time per application (s) 178.5 ± 57.83
PV potentials; n (%) 4098 (61.0)
TTE (s) 52.9 ± 37.02
Temperature at PVI (°C) − 33.6 ± 9.92
PVI with 1st application; (n/%) 75.8 (6381)
Minimum temperature (°C) − 45.4 ± 8.20
Rewarming time (s) 38.7 ± 20.15
Per vein analysis LSPV A LIPVB RSPVC RIPVD
Total veins (n) 1537 1534 1691 1660
Total applications (n) 2828 2766 3059 3148
Applications per vein 1.8 ± 1.07 1.8 ± 1.01 1.8 ± 1.06 1.9 ± 1.17
Time per application (s) 179.7 ± 56.14BD 179.7 ± 59.74AD 173.6 ± 58.76* 179.4 ± 57.65AB
PV potentials (%) 1110 (72.4)* 967 (63.2) * 997 (59.2) * 834 (50.6) *
TTE (s) 52.1 ± 34.14BC 51 ± 34.3AC 49.0 ± 38.88AB 59.0 ± 39.62*
Temperature at PVI (°C) − 35.2 ± 9.29D − 31.3 ± 9.7* − 33.2 ± 10.78D − 34.4 ± 9.43C
PVI with 1st application; n (%) 1487 (77.67)BCD 1455 (78.35)AC 1610 (75.0)ABD 1552 (73.7)AD
Total cryotherapy time (s) 330.3 ± 173.92BCD 323.8 ± 162.16AC 314.0 ± 174.86AB 340.4 ± 193.07A
Minimum temperature (°C) − 46.4 ± 8.04* − 43.4 ± 7.84* − 47.3 ± 8.07* − 44.4 ± 8.20*
Rewarming time (s) 43.3 ± 22.82* 36.7 ± 18.94D 41.0 ± 19.63* 34.3 ± 17.80B

Differences on averages by patient-location, since multiple applications could have received at each patient-location (on average 1.8 applications over each location) are shown, using a mixed-effects model and adjusting for multiple comparisons (Bonferroni). Locations with a significantly different value (p < 0.001) differing from all other locations are flagged with an asterisk. When the average compared is not different from another location (p > 0.05), the value is labeled with a letter corresponding to the non-significant locations (labeled from left to right: A, B, C, D).

Quantitative data are the mean ± standard deviation.

PV pulmonary vein, PVI PV isolation, TTE time to effect, LSPV left superior pulmonary vein, LIPV left inferior pulmonary vein, RSPV right superior pulmonary vein, RIPV right inferior pulmonary vein.