Table 2.
Single and total apheresis yield by weight, stratified by disease
| 1st cycle |
2nd cycle |
3rd cycle |
|||||
|---|---|---|---|---|---|---|---|
| Disease | n | Yield | n | Yield | n | Yield | Total yield |
| ADA-SCID | 4 | 11.5 (1.8−30.9) | 3 | 8.2 (1.5−18.8) | 1 | 9.1 | 27.7 (3.3−34.7) |
| β-thalassemia | 7 | 31.1 (7.5−53.2) | 3 | 23.1 (15.5−30.9) | − | 45.6 (30.6−53.2) | |
| MLD | 10 | 15.5 (5.2−36.7) | 6 | 24.1 (20.4−43.6) | − | 36.5 (5.2−57.9) | |
| MPSIH | 8 | 18.2 (1.6−24.3) | 8 | 23.9 (12.3−34.2) | 2 | 13.0 (6.3−19.6) | 45.4 (31.0−55.3) |
| WAS | 16 | 20.2 (0.7−42.0) | 12 | 21.6 (9.0−35.4) | 2 | 12.7 (9.3−16.2) | 34.4 (18.7−63.8) |
| Total | 45 | 18.3 (0.7−53.2) | 32 | 32 (1.5−43.6) | 5 | 9.3 (6.3−19.6) | 37 (3.3−63.8) |
Cell counts (×106 CD34+ cells/kg) are reported as median and range (in parentheses). The number of patients is reported for each apheresis procedure.