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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2021 Feb 27;20(2):342–352.e5. doi: 10.1016/j.cgh.2021.02.035

Table 3.

Temporal trends in healthcare utilization rates of period-prevalent patients per 1000 enrolled person-years, by study year in Medicare

Period prevalent patients, N 2008
4,728
2009
4,776
2010
4,883
2011
5,318
2012
5,388
2013
5,635
2014
6,604
2015
6,958
APC (95% CI)
Healthcare services* per 1000 enrollee years
Hospitalizations 75.2 85.3 79.6 88.2 75.9 74.9 76.2 86.4 0.2 (−1.4, 1.8)
Emergency room visits 17.3 12.4 10.8 12.7 11.8 14.2 13.5 18.6 2.8 (−1.1, 6.8)
Outpatient visits 468.6 502.1 500.3 523.7 553.9 578.5 613.1 628.6 4.4 (3.7, 5.0)
Diagnostic procedures per 1000 enrollee years
Thorax CT or X-ray 785.2 867.8 781.4 809.9 819.9 844.3 838.1 849.1 0.7 (0.2, 1.3)
Barium swallow 279.9 311.6 299.6 289.5 293.2 303.1 294.4 309.5 0.6 (−0.3, 1.4)
Esophagoscopy & UE 847.9 907.6 840.4 870.4 833.5 872.0 849.2 835.9 −0.5 (−0.9, 0.0)
Manometry 90.9 92.4 90.4 99.7 98.1 113.3 122.0 132.5 6.1 (4.7, 7.6)
Reflux monitoring 18.6 20.5 23.1 25.4 37.2 48.8 54.6 59.9 20.6 (17.6, 23.7)
Therapeutic procedures per 1000 enrollee years
Pneumatic dilation 13.6 12.6 8.0 10.3 9.5 10.9 12.7 10.4 −1.1 (−5.3, 3.2)
Surgical myotomy 9.6 21.1 20.5 17.2 19.3 22.6 23.3 23.4 7.2 (3.7, 10.7)
Anti-reflux surgery 15.7 29.7 27.0 32.9 32.2 38.1 35.0 39.4 8.7 (5.9, 11.5)
Esophagectomy 1.9 3.2 2.1 2.4 1.8 2.2 1.7 1.4 −6.1 (−15.0, 3.7)
Unlisted procedure of esophagus 3.7 2.9 2.8 4.2 6.8 5.5 5.3 11.3 19.7 (12.1, 27.8)
Dispensed medications, prescriptions per 1000 enrollee years
CCBs 900.8 867.8 948.2 1,081.8 1,133.3 1,191.3 1,123.3 1,144.6 4.1 (3.7, 4.6)
PPIs 1,114.8 1,630.1 1,280.9 1,476.9 1,877.3 2,311.2 2,285.3 2,418.6 11.1 (10.8, 11.5)
Nitrates 634.5 422.3 407.1 295.8 244.4 308.2 311.5 346.5 −8.2 (−8.8, −7.5)
Anticholinergics 115.6 74.7 31.6 4.7 1.1 6.9 9.5 5.9 −43.5 (−45.7, −41.3)
Antidepressants & neuromodulators 1,251.6 1,394.4 1,427.7 1,642.0 1,795.1 1,894.1 2,257.5 2,484.1 10.5 (10.1, 10.9)
Opioid medications 582.4 582.6 701.0 849.9 905.7 1,057.8 1,222.1 1,313.0 13.5 (12.9, 14.0)
Pro-motility drugs 302.7 180.3 115.3 134.0 76.3 104.4 87.1 45.6 −19.9 (−21.0, −18.9)

Abbreviations: GI, gastrointestinal; EKG, electrocardiogram; UE, upper endoscopy; CCBs, calcium channel blockers; PPIs, proton pump inhibitors

*

Hospitalizations, emergency department visits, and office visits all required a diagnosis of achalasia in the first or second diagnosis position Period prevalent includes patient with prevalent disease on January 1st of a given year and incident cases that develop achalasia in that calendar year.

Peroral endoscopic myotomy (POEM) does not have a specified CPT code, currently billed as unlisted procedure of the esophagus