Table 3.
Incidence Rates of the Muscular Events in the Primary Prevention Cohorts Before and After Propensity Score Matching
Number (%) of muscular events | Total person-years of follow-up | Incidence rate per 1,000 person-years | ||||
---|---|---|---|---|---|---|
Exposed | Comparator | Exposed | Comparator | Exposed | Comparator | |
Low-intensity statin therapy | ||||||
Pravastatin vs simvastatin (ref) | ||||||
Crude | 82 (0.8) | 2,205 (1.2) | 7,584 | 143,220 | 10.8 | 15.4 |
PS-matched | 82 (0.8) | 98 (1.0) | 7,577 | 7,852 | 10.8 | 12.5 |
Moderate- to high-intensity statin therapy | ||||||
Rosuvastatin vs atorvastatin (ref) | ||||||
Crude | 101 (1.4) | 854 (1.0) | 5,648 | 64,369 | 17.9 | 13.3 |
PS-matched | 100 (1.4) | 86 (1.2) | 5,628 | 5,658 | 17.8 | 15.2 |
Simvastatin vs atorvastatin (ref) | ||||||
Crude | 2,456 (1.5) | 957 (0.9) | 124,546 | 78,697 | 19.7 | 12.2 |
PS-matched | 483 (1.3) | 368 (1.0) | 29,222 | 29,708 | 16.5 | 12.4 |
Ref reference, PS propensity score