Fig. 1. Isolates of different cystic fibrosis (CF) status and country of isolation are dispersed across MAB dominant circulating clones.

Single-copy core phylogenetic trees for a M. massiliense and b M. abscessus, including one isolate per patient. Trees were constructed using RAxML⁶⁶ after recombination removal. The inner ring indicates the country of isolation, and the outer ring indicates whether the sample originated from a person with a diagnosis of CF (black) or without CF (white). DCCs (Supplementary Table 3; Supplementary Fig. 1) with at least 10 isolates of M. abscessus (A1-A6) or M. massiliense (M1-M4) are numbered in descending order of size with bold branches. DCCs A1, A2, and M1 corresponded to M. abscessus clusters 1 and 2, and M. massiliense cluster 1, respectively, from Bryant et al. ¹⁴. The corresponding data for M. bolletii is shown in Supplementary Fig. 1a.