Table 1.
Patient characteristics (per jaw).
| Variable | Number of jaws/mean ± standard devision | MRONJ (−) | MRONJ (+) | |
|---|---|---|---|---|
| Age (years) | 62 ± 11.8 | 61.6 ± 11.8 | 65.9 ± 10.7 | |
| Sex | Female | 215 | 193 | 22 |
| Male | 146 | 135 | 11 | |
| Primary site | Upper jaw | 177 | 164 | 13 |
| Lower jaw | 184 | 164 | 20 | |
| Smoking habit | (−) | 300 | 270 | 30 |
| (+) | 57 | 54 | 3 | |
| Diabetes | (−) | 321 | 294 | 29 |
| (+) | 38 | 34 | 4 | |
| Corticosteroid | (−) | 320 | 290 | 30 |
| (+) | 41 | 38 | 3 | |
| Leukocytes (/μL) | 2443 ± 2091 | 2433 ± 2066 | 2537 ± 2353 | |
| Albumin (g/dL) | 2.96 ± 0.762 | 2.95 ± 0.773 | 3.06 ± 0.641 | |
| Sort of BMA | BP | 161 | 149 | 12 |
| Dmab | 189 | 169 | 20 | |
| BP → Dmab | 11 | 10 | 1 | |
| Duration of administration (days) | 243 ± 631 | 221 ± 602 | 455 ± 850 | |
| Number of teeth | 11.2 ± 3.58 | 11.3 ± 3.57 | 10.5 ± 3.63 | |
| Symptom of local infection | (−) | 331 | 311 | 20 |
| (+) | 30 | 17 | 13 | |
| Teeth that can be a source of infection | (−) | 171 | 162 | 9 |
| (+) | 190 | 166 | 24 | |
| Tooth extraction during BMA therapy | (−) | 334 | 306 | 28 |
| (+) | 27 | 22 | 5 |
Teeth that can be a source of infection:
periapical lesion (> 3 mm) or alveolar bone loss (> 1/2) or probing pocket depth (> 4 mm).