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(A) Right ventricular pressure (RVSP) in HPH and healthy rats. (B) Right ventricular hypertrophy (RVHI) was measured using the following formula: RVHI = right ventricle / (left ventricle + ventricular septum). (C) Haematoxylin and eosin (HE) staining of pulmonary arterial sections. (D) Wall area (WA) was calculated using the following equation: WA = 1 – lumen area / vessel total area; *P<0.05 and **P<0.01 versus healthy group.
