Figure 6.

Overlap model for the effectiveness of stimuli in generating responses. (A) Schematic of the overlap model: the laser profile is approximated by a two-dimensional Gaussian and the dendrite modeled by a cylinder with radius R. (B) Top-down view of the two laser profiles projected onto proximal and distal dendrites. Proximal dendrites have radius 500 nm, and distal dendrites have radius 200 nm. (C–H) Theoretical curves (lines) superimposed on the measured peak ΔF/F for somal (C and D), proximal dendrite (E and F), and distal dendrite (G and H) stimulation. Dashed lines represent the surface model, and dotted line represents the volume model. Model parameters are listed in Tables S10 and S11. To see this figure in color, go online.