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. 2021 Jun 30;120(16):3409–3417. doi: 10.1016/j.bpj.2021.06.026

Figure 8.

Figure 8

Effects of glutamate release at different nanodomains. The red circle highlights the area of nanodomain 1 containing 41 AMPARs. The yellow circle highlights the area of nanodomain 1 containing 27 AMPARs. “pre” shows the image before glutamate release; the maximal projection image of 4 ms after glutamate release is shown to the right. “Same release” shows a snapshot of the state of the synapse at 50 ms after glutamate release; the maximal projection image of 4 ms after glutamate release is at the center of the red circle. (Top right) Number of open AMPARs under the same release condition. “Random release” shows a snapshot of the state of the synapse at 50 ms after glutamate release; the maximal projection image of 4 ms after glutamate release is at the center of the yellow circle. The number of open AMPARs under the random release condition is shown. No difference in PPR is observed in either condition (middle graph). To see this figure in color, go online.