Table 1.
Demographic features of T4 colon cancer
| Variable | Total | Stage |
P-value | |
|---|---|---|---|---|
| T4a | T4b | |||
| No. of patients | 82 | 69 | 13 | |
| Age (yr) | 67.8 ± 13.1 | 68.0 ± 12.8 | 66.9 ± 14.8 | 0.778 |
| Sex | 0.008 | |||
| Male | 47 (57.3) | 44 (63.8) | 3 (23.1) | |
| Female | 35 (42.7) | 25 (36.2) | 10 (76.9) | |
| Body mass index (kg/m2) | 23.0 ± 3.2 | 23.1 ± 3.3 | 22.2 ± 2.6 | 0.329 |
| CCI | 0.492 | |||
| ≥4 | 35 (42.7) | 30 (43.5) | 5 (38.5) | |
| <4 | 47 (57.3) | 39 (56.5) | 8 (61.5) | |
| Location of tumor | 0.062 | |||
| Right | 51 (62.2) | 40 (58.0) | 11 (84.6) | |
| Left | 31 (37.8) | 29 (42.0) | 2 (15.4) | |
| Differentiation | 0.059 | |||
| Well | 3 (3.7) | 1 (1.4) | 2 (15.4) | |
| Moderate | 72 (87.8) | 62 (89.9) | 10 (76.9) | |
| Poorly | 3 (3.7) | 2 (2.9) | 1 (7.7) | |
| Othersa | 4 (4.9) | 4 (5.8) | 0 (0) | |
| Tumor size (cm) | 6.0 ± 1.9 | 6.0 ± 1.9 | 6.0 ± 2.1 | 0.974 |
| N stage | 0.193 | |||
| 0 | 32 (39.0) | 24 (34.8) | 8 (61.5) | |
| 1 | 30 (36.6) | 27 (39.1) | 3 (23.1) | |
| 2 | 20 (24.4) | 18 (26.1) | 2 (15.4) | |
| Invasion | ||||
| Lymphatic | 72 (87.8) | 59 (85.5) | 13 (100) | 0.159 |
| Vascular | 41 (50.0) | 35 (50.7) | 6 (46.2) | 0.500 |
| Perineural | 24 (29.3) | 19 (27.5) | 5 (38.5) | 0.314 |
| CEA (ng/mL) | 21.3 ± 58.8 | 11.7 ± 28.8 | 60.2 ± 117.5 | 0.003 |
| Operative technique | 0.044 | |||
| Open | 30 (36.6) | 22 (31.9) | 8 (61.5) | |
| Laparoscopic | 52 (63.4) | 47 (68.1) | 5 (38.5) | |
| Adjuvant chemotherapy | 68 (82.9) | 56 (81.2) | 12 (92.3) | 0.299 |
| Recurrence | 23 (28.0) | 20 (29.0) | 3 (23.1) | 0.475 |
| Local | 4 (4.9) | 4 (5.8) | 0 (0) | 0.494 |
| Distant | 21 (25.6) | 18 (26.1) | 3 (23.1) | 0.562 |
| Expire | 27 (32.9) | 23 (33.3) | 4 (30.8) | 0.566 |
Values are presented as number only, mean±standard deviation, or number (%).
CCI, Charlson comorbidity index; CEA, carcinoembryonic antigen.
a
Mucinous carcinoma and signet ring cell.