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. 2021 Jul 6;120(16):3382–3391. doi: 10.1016/j.bpj.2021.06.031

Figure 4.

Figure 4

Boxplot of length of LCRs for positive LCRs in FG Nups, negative LCRs in FG Nups, positive LCRs in DisProt, and negative LCRs in DisProt. All of the LCRs above two amino acids in length are considered in these data sets. (A) Positive LCRs in FG Nups show a significant difference in terms of average and range from negative LCRs in FG Nups and positive and negative LCRs in DisProt. (B) lpLCRs in FG Nups are removed from the data, and the rest of the data look similar to the other three segments of data. This means that the major difference that can be observed in plot (A) between positive LCRs in FG Nups and the other three segments of data is due to presence of the lpLCRs in FG Nups, which mainly form the outlier section of positive LCRs. Other than that, the rest of the positive LCRs in FG Nups have similar characteristics to the other three segments of data. This implies that what differentiates FG Nups from DisProt in terms of charge distribution is the presence of lpLCRs. These patterns are virtually exclusive to FG Nups and are not observed in DisProt. AVG, average; STD, standard deviation. To see this figure in color, go online.