Figure 6.
The combined treatment of hydralazine and enzalutamide augmented DNA damage (here represented by the tail moment measurement) in PCa (prostate cancer) cells. The presented data are representative of at least 500 cells analysed. The mean ± standard deviation were as follows: LNCaP V—0.96 ± 5.33; LNCaP H—4.23 ± 10.8; LNCaP E—6.19 ± 13.9; LNCaP H+E—4.53 ± 12.9; PC-3 V—0.36 ± 2.84; PC-3 H—3.36 ± 10.84; PC-3 E—5.35 ± 14.18; PC-3 H+E—5.34 ± 14.67; C4-2 V—0.66 ± 3.31; C4-2 H—4.74 ± 13.33; C4-2 E—4.45 ± 12.46; C4-2 H+E—7.42 ± 16.85 (V—vehicle, H—hydralazine, E—enzalutamide, H+E—combination of hydralazine and enzalutamide).