Table 1.

Correlation of miRNA levels in liquid biopsies and in matched tissue samples.

miRNA	Tumor Type	Expression in Tissue	Expression in Biofluids	References
miR-196	Gastric cancer	Upregulated	Upregulated in plasma	[48,67]
miR-206	Gastric cancer	Downregulated	Downregulated in serum	[49,68]
miR-21	Gastric cancer	Upregulated	Downregulated in gastric juice	[61,69]
miR-106	Gastric cancer	Upregulated	Downregulated in gastric juice	[61,70]
miR-21	Glioma	Upregulated	Upregulated in cerebrospinal fluid	[65,71]
miR-21	Non-small cell lung cancer	Upregulated	Upregulated in plasma	[51,72]
miR-20a miR-223-3p miR-221-3p	Non-small cell lung cancer	Upregulated	Upregulated in plasma	[51,73,74,75]
miR-145	Non-small cell lung cancer	Downregulated	Upregulated in plasma	[51,76]
miR-34b-5p, miR-34c-5p, miR-455-5p miR-141-3p, miR-205-5p miR-21-5p, miR-148a-3p	Thymic Epithelial Tumors	Upregulated Upregulated	Undetectable in plasma Upregulated in plasma	[25,55]
miR-214	Breast cancer	Downregulated	Upregulated in serum	[54,77]
miR-190	Breast cancer	Downregulated	Downregulated in serum	[53,78]
miR-424 miR-125b	Breast cancer	Downregulated	Upregulated in urine and serum	[62,79,80]
miR-let7a	Breast cancer	Downregulated	Downregulated in urine and serum	[62,81]
miR-19a miR-20	Colorectal carcinoma	Upregulated	Upregulated in serum	[56,82]
miR-103	Colorectal carcinoma	Upregulated	Upregulated in serum	[57,83]
microRNA-200 family (miR-200a, miR-200b, miR-200c, miR-141 and miR-429)	Colorectal carcinoma	Upregulated Downregulated in the invasive front of tumor with degraded basement membrane	Upregulated in serum	[58,84,85]
miR-142-3p and miR-223-3p	Prostate cancer	Upregulated	Upregulated in seminal fluid	[64,86,87]
miR-30a-5p	Ovarian cancer	Upregulated	Upregulated in urine	[52,63]