Table 1.

Comparison of change in all variables over the treatment period.

Characteristics	Baseline	After 8 Weeks	After 12 Weeks	After 24 Weeks	Baseline	After 8 Weeks	After 12 Weeks	After 24 Weeks	Baseline	After 8 Weeks	After 12 Weeks	After 24 Weeks
	Subject 1				Subject 2				Subject 3
Sweat chloride (mEq/L)	110	26	46	46	103	40	34	31	85	48	30	29
ppFEV1 (%)	26.0	39.0	44.0	41.0	25.8	34.2	34.0	32.0	29.0	48.9	53.5	53.6
BMI (Kg/m2)	20.3	20.9	21.6	21.2	24.4	25.8	25.7	26.2	19.5	20.5	21.6	22.6
6MWT (m)	360	558	545	521	403	480	495	485	500	544	560	572
Oxigen saturation	84	89	96	98	75	78	81	91	82	89	93	95
Heart rate	138	139	120	110	119	129	145	122	154	141	130	135
CFQ-R 14 + domain
Physical functioning	16.67	62.50	62.50	58.33	25.00	41.67	100.00	58.33	12.50	62.50	75.00	100.00
Role perception	91.67	91.67	100.00	91.67	66.67	83.33	100.00	83.33	58.33	83.33	83.33	100.00
Vitality	41.67	83.33	83.33	75.00	25.00	50.00	83.33	75.00	25.00	75.00	75.00	83.33
Emotion	73.33	100.00	100.00	93.33	40.00	46.67	46.67	66.67	46.67	66.67	60.00	73.33
Social perception	72.22	83.33	88.89	77.78	22.22	50.00	38.89	44.44	50.00	55.56	77.78	88.89
Body image	88.89	100.00	100.00	100.00	100.00	55.56	100.00	100.00	66.67	77.78	88.9	100.00
Eating disturbance	100.00	100.00	100.00	100.00	55.56	55.56	100.00	66.67	55.56	100.00	100.00	100.00
Treatment burden	33.33	44.44	55.56	55.56	77.78	77.78	77.78	77.78	22.22	55.56	66.67	77.78
Health perception	55.56	66.67	66.67	55.56	66.67	88.89	88.89	100.00	11.11	66.67	66.67	88.89
Weight	66.67	100.00	100.00	100.00	100.00	66.67	66.67	100.00	33.33	100.00	100.00	100.00
Respiratory symptoms	44.44	83.33	83.33	83.33	50.00	72.22	83.33	77.78	44.44	83.33	83.33	83.33
Digestive symptoms	88.89	100.00	100.00	88.89	88.89	77.78	88.89	77.78	88.89	100.00	77.78	100.00