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Caspase 3 activities in (A) HCT116 and (B) MDA-MB-231-Luc treated with costunolide (COS), doxorubicin (DOX), costunolide + doxorubicin (COS + DOX), costunolide-nanoparticles (COS-NPs), and costunolide-nanoparticles + doxorubicin (COS-NPs + DOX). Values are presented as mean ± SD. ** p < 0.01 and *** p < 0.001.
