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. 2021 Aug 6;13(16):3976. doi: 10.3390/cancers13163976

Table 3.

Cox regression analysis for investigating the correlation between USP19 expression and BRCA1/2 mutation and progression-free survival.

Cohort Model Variable Coefficient Exp (coef.) = Hazard Ratio SE
(coef.)
p-Value
This study
(n = 42)
USP19 exp. USP19 −0.040 0.96 0.014 0.0048 *
BRCA mutation BRCA −0.15 0.86 0.35 0.67
USP19 exp. + BRCA mutation USP19 # −0.056 0.95 0.018 0.0018 *
BRCA 0.73 2.07 0.45 0.10
TCGA
(n = 134)
USP19 exp. USP19 −0.014 0.99 0.0085 0.091
BRCA mutation BRCA −0.62 0.54 0.35 0.081
USP19 exp. + BRCA mutation USP19 # −0.023 0.98 0.0097 0.017 *
BRCA −0.89 0.41 0.38 0.018 *

# USP19 expression after adjusting the BRCA1/2 mutation status. * p < 0.05.