Table 3.
Cohort | Model | Variable | Coefficient | Exp (coef.) = Hazard Ratio | SE (coef.) |
p-Value |
---|---|---|---|---|---|---|
This study (n = 42) |
USP19 exp. | USP19 | −0.040 | 0.96 | 0.014 | 0.0048 * |
BRCA mutation | BRCA | −0.15 | 0.86 | 0.35 | 0.67 | |
USP19 exp. + BRCA mutation | USP19 # | −0.056 | 0.95 | 0.018 | 0.0018 * | |
BRCA | 0.73 | 2.07 | 0.45 | 0.10 | ||
TCGA (n = 134) |
USP19 exp. | USP19 | −0.014 | 0.99 | 0.0085 | 0.091 |
BRCA mutation | BRCA | −0.62 | 0.54 | 0.35 | 0.081 | |
USP19 exp. + BRCA mutation | USP19 # | −0.023 | 0.98 | 0.0097 | 0.017 * | |
BRCA | −0.89 | 0.41 | 0.38 | 0.018 * |
# USP19 expression after adjusting the BRCA1/2 mutation status. * p < 0.05.