Table 3.

Selection of genes associated with CDR and suggested molecular mechanisms.

Gene	GWAS Identified	Suggested Mechanism	Reference
ABCA1	Springelkamp et al., 2017 [59]	Normal Function and Cell Death of Retinal Ganglion Cells	Chen et al., 2014 [64]
ELN	Han et al., 2021 [61]	Alteration to Normal Function of Elastin, Leading to Optic Nerve Head Degeneration	Gelman et al., 2010 [26]
ASAP1	Alipanahi et al., 2021 [65]	Glial Cell-Mediated Retinal Ganglion Cell Loss	García-Bermúdez et al., 2021 [66]
ATOH7	Nannini et al., 2018 [60]	Alteration to Müller Cel Differentiation and Retinal Ganglion Cell Genesis	Miesfeld et al., 2020 [25]